Eriksen, 30, was playing for his country for the first time since his cardiac arrest at euro 2020 last June.
The midfielder, who has since joined Premier League club Brentford, made a terrific end into the top corner.
“I was happy the ball came to me,” said Eriksen.
“I thought it absolutely was a stunning end and to start out my international comeback like this can be an ideal approach.”
Eriksen may have had a second goal when he turned outside the area, but his curling strike hit a post.
Tottenham’s Steven Bergwijn did score twice for Netherlands, with Nathan Ake and Memphis Depay also on the scoresheet, whereas Jannik Vestergaard netted Denmark’s first goal.
But it was Eriksen who was the centre of attention – coming on to win his one hundred and tenth cap as a second-half substitute to large cheers from the group at Johan Cruyff Arena in capital of The Netherlands, home of his former club Ajax.
Netherlands manager louis van Gaal was among those to clap Eriksen, who applauded reciprocally.
And just 2 minutes later he sent his team-mates and fans into raptures, rattling home a confident finish from Andreas Skov Olsen’s cutback.
“It has always been pretty place and today is a fair more special place for me to play my first international game during this sports stadium,” other Eriksen, despite someone throwing a coin towards him during his post-match interview.
Denmark next face serbia in a very friendly on Tues (17:00 BST).
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